Figure 5.

Six of 12-week and 9 of 12-week Abdominal Score response rates (pooled population). The 6 of 12- or 9 of 12-week Abdominal Score response was defined as achieving weekly Abdominal Score response with ≥2-point reduction in a week for ≥6 or 9 weeks of the first 12 weeks of treatment. Response rates were analyzed using the Pearson χ² test with a worst-case imputation approach (patients with missing data included and assumed to have no response). P values were obtained from Pearson χ² tests. The Abdominal Score was defined as the average of weekly scores for abdominal pain, discomfort, and bloating. AS, Abdominal Score.