Figure 3.

Radiomics signature construction. (A) Tuning parameter selection (λ) with 10-fold cross-validation in the LASSO logistic regression model. The dotted vertical line is drawn at the optimal λ value by minimum criteria, which is 0.063 with log (λ) = –2.761. (B) LASSO coefficient profiles of the candidate variables. (C) The histogram presents the 14 selected features and their corresponding coefficients in the radiomics signature. Features are all shown in the format of "filter_feature class_feature name". Refer to Supplementary Table 2, http://links.lww.com/CM9/B751 for the full feature names of the abbreviations. LASSO: Least absolute shrinkage and selection operator.