Fig. 2.

Heat map of baseline lipids/apolipoproteins, lipoproteins, inflammatory, and metabolic biomarker concentrations in relation to incident CHD. Models were adjusted for baseline age, race, education, menopause, postmenopausal hormone use, and randomized treatment assignment (model 1). To adjust for confounding among large, medium, and small LDL particles, their models included model 1 variables plus the other LDL subclasses (small, medium, and large LDL particle concentrations). The left panel shows the Cox proportional HRs (in descending order of magnitude of risk) for risk factors in association with premature (green bars) and nonpremature (black bars) incident CHD. HR for biomarkers based on per SD increment of plasma concentration. The right panel shows the logarithm of P value for the association of risk factors with baseline age category (<65 years vs ≥ 65 years) in descending order of strength of association (from brown to green in color).