Extended Data Fig. 7. Structure and sequence-based differentiation of UmbB-interacting and non-interaction ALF repeats.

a, Probability sequence logo generated from an alignment of positions 1-8 of the UmbB1-interacting ALF repeats of UmbC1, compared to the analogous positions in AFL6. Positions located at the interaction interface and which have non-conservative substitutions in ALF6 are highlighted in blue. b, Predicted structural models for the interaction between each ALF repeat of UmbC1 with UmbB1, and RoseTTAFold2 predicted error scores (PAE) calculated for models of the ALF repeats of each S. coelicolor UmbC protein interacting with its cognate UmbB. PAE values: <10, high confidence; <20, moderate confidence; >20, low confidence³⁸. N/A, no interaction predicted.