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. 2024 Apr 17;629(8010):165–173. doi: 10.1038/s41586-024-07298-z

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 8 — a,b, Representation of single-nucleotide variants (SNVs) by chromosomal position, frequency, and density in E. coli Δung following 60 min induction of expression of the deaminase toxin domain from UmbC1 (a), or the equivalently-treated vector control strain (b). c, Frequency of the indicated substitutions among the SNVs shown in (a). d, Probability sequence logo of the region flanking mutated cytosines among the SNVs shown in (a).