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. 2024 May 1;14:10024. doi: 10.1038/s41598-024-60623-4

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Mediating role of infarct volume on the effect of global hyperperfusion on worse 90-day mRS. Unstandardized and standardized regression coefficients for each path of the mediation model are presented. The 95% bootstrap confidence intervals for the unstandardized coefficients are provided. ^†Controlled for age, sex, smoking, initial NIHSS score, occlusion site of M2, intravenous thrombolysis, and hemorrhagic transformation. ^‡Controlled for age, sex, hypertension, active cancer, initial diastolic blood pressure, initial NIHSS score, stroke etiology, intravenous thrombolysis, and hemorrhagic transformation. ***p < 0.001; **p < 0.01; *p < 0.05. B unstandardized coefficient, β standardized coefficient, mRS modified Rankin Scale, NIHSS National Institutes of Health Stroke Scale.