Table 2.
Linear regression analysis of factors associated with infarct volume.
| Univariate analysis | Multivariate analysis† | |||||
|---|---|---|---|---|---|---|
| B (SE) | β | p value | B (SE) | β | p value | |
| Age | 0.004 (0.005) | 0.061 | 0.49 | − 0.001 (0.004) | − 0.024 | 0.73 |
| Male sex | 0.146 (0.143) | 0.090 | 0.31 | 0.045 (0.126) | 0.028 | 0.72 |
| Ever smoking | 0.406 (0.170) | 0.205 | 0.019 | 0.261 (0.154) | 0.132 | 0.092 |
| Initial NIHSS | 0.052 (0.010) | 0.423 | < 0.001 | 0.031 (0.009) | 0.253 | 0.001 |
| M2 occlusion‡ | − 0.387 (0.162) | − 0.206 | 0.019 | − 0.400 (0.137) | − 0.212 | 0.004 |
| Intravenous thrombolysis | 0.429 (0.145) | 0.253 | 0.004 | 0.306 (0.120) | 0.181 | 0.012 |
| Hemorrhagic transformation | 0.618 (0.132) | 0.382 | < 0.001 | 0.515 (0.115) | 0.318 | < 0.001 |
| Hyperperfusion | ||||||
| No hyperperfusion | Reference | Reference | ||||
| Focal hyperperfusion | 0.181 (0.153) | 0.103 | 0.24 | 0.069 (0.129) | 0.039 | 0.59 |
| Global hyperperfusion | 0.799 (0.179) | 0.388 | < 0.001 | 0.532 (0.163) | 0.258 | 0.001 |
†R2 = 0.395 and p < 0.001 for the linear regression equation. The multivariate model incorporated the following variables: age, sex, smoking, initial NIHSS score, occlusion site, intravenous thrombolysis, hemorrhagic transformation, and the degree of hyperperfusion.
‡Internal carotid artery and M1 occlusions were grouped together versus M2 occlusion.
B unstandardized coefficient, β standardized coefficient, NIHSS National Institutes of Health Stroke Scale, SE standard error.