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. 2024 May 1;20(5):753–763. doi: 10.5664/jcsm.10998

Table 3.

Sleep diary outcomes.

Measure Treatment After Placebo Run-In After 1 Week of Dosing After 2 Weeks of Dosing F P
Sleep quality CBD 2.8 (1) 3.4 (1) 3 (1) 8.1(2, 582.5) <.001*
PLA 2.9 (1.1) 2.9 (1) 3.1 (0.9)
No. of awakenings CBD 2.1 (1.9) 1.5 (1.6) 1.5 (1.7) 0.4(2, 569.1) .69
PLA 1.7 (1.3) 1.4 (1.7) 1.3 (1.3)
WASO (decimal hours) CBD 0.6 (0.5) 0.5 (0.6) 0.6 (0.7) 1.3(2, 544.1) .27
PLA 0.6 (0.7) 0.4 (0.7) 0.4 (0.6)
SE (%) CBD 86.8 (3.1) 86.4 (4.2) 87 (2.7) 1.5(2, 567.1) .22
PLA 87 (3.8) 85.9 (6) 85.7 (6.3)
SOL (decimal hours) CBD 0.82 (0.9) 0.6 (0.7) 0.6 (0.7) 0.6(2, 576) .63
PLA 0.9 (0.7) 0.6 (0.8) 0.5 (0.4)
TST (decimal hours) CBD 7.94 (1.5) 8 (1.6) 8 (1.5) 1.8(2, 566.3) .17
PLA 8 (1.5) 7.8 (1.8) 7.6 (1.8)

Weekly sleep diary–derived raw means, standard deviation, and interaction terms are shown. *Statistically significant effect (P < .05). “No. of awakenings” indicates number of awakenings after sleep onset. CBD = cannabidiol treatment group, PLA = placebo treatment group, SE = sleep efficiency, SOL = sleep-onset latency, TST = total sleep time, WASO = wake after sleep onset.