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[Preprint]. 2024 Apr 18:rs.3.rs-4189278. [Version 1] doi: 10.21203/rs.3.rs-4189278/v1

Table 2.

Hospitalization Events and Outcomes

Variable Total
N=321
Peak Edema Timing
Acute

N=104
(32.4)
Average

N=114
(35.5)
Subacute

N=103
(32.1)
p
Mass Effect
 Hemorrhagic Transformation
  No Hemorrhage 87 (27.1) 37 (35.6) 31 (27.2) 19 (18.4) 0.02
  Parenchymal Hemorrhage 42 (13.1) 21 (20.2) 12 (10.5) 9 (8.7) 0.03
  Petechial Hemorrhage 216 (67.3) 56 (53.8) 79 (69.3) 81 (78.6) <0.01
 Midline Shift (MLS)
  Substantial MLS 180 (56.1) 54 (51.9) 63 (55.3) 63 (61.2) 0.40
  Maximum MLS (mm) 6.7 ±4.2 6.4 ±4.2 6.4 ±3.9 7.3 ±4.5 0.22
  Time to Maximum MLS (hr) 87.1 ±60.9 39.3 ±34.1 69.7 ±21.0 154.7 ±51.9 <0.01
 Pineal Gland Shift (PGS)
  PGS ≥ 4mm 122 (38.0) 32 (30.8) 42 (36.8) 48 (46.6) 0.06
  Maximum PGS (mm) 3.8 ±2.5 3.5 ±2.3 3.7 ±2.3 4.3 ±2.9 0.06
  Time to Maximum PGS (hr) 82.7 ±66.3 46.6 ±56.5 69.4 ±42.4 133.7 ±66.5 <0.01
 Decompressive Hemicraniectomy 69 (21.5) 40 (38.5) 22 (19.3) 7 (6.8) <0.01
 Osmotic Therapy 149 (46.4) 56 (53.8) 49 (43.0) 44 (42.7) 0.18
 Peak Edema Trajectory Cluster - - - - <0.01
  Fast 122 (38.0) 81 (77.9) 34 (29.8) 7 (6.8) -
  Medium 163 (50.8) 21 (20.2) 74 (64.9) 68 (66.0) -
  Slow 36 (11.2) 2 (1.9) 6 (5.3) 28 (27.2) -
Discharge Outcomes
 Unfavorable Disposition 147 (45.8) 52 (50.0) 54 (47.4) 41 (39.8) 0.31
 Favorable Disposition 174 (54.2) 52 (50.0) 60 (52.6) 62 (60.2) 0.31

Parentheses indicate percentages for categorical variables; ± indicate standard deviations for continuous variables.