Figure 5.

Plasmodium yoelii-infected hypertensive mice showed severe liver dysfunction. Ten-week-old BPN and BPH females (n = 5) were infected with P. yoelii. Serum samples were collected after 15 d p.i. and analyzed for (A) serum aspartate aminotransferase (AST), (B) serum alkaline phosphatase (ALP), and (C) liver histology: hematoxylin-eosin (H&E) and Periodic acid-Schiff (PAS) staining. (D) Serum total bile acid (TBA), (E) serum cholesterol. (F) Spleen histology—H&E. Data represented as mean ± SEM from 3 independent experiments. *P < .05, **P < .01, and ***P < .001.