Skip to main content
. 2015 Apr 21;2015(4):CD009699. doi: 10.1002/14651858.CD009699.pub2

Comparison 1. Liberal versus restrictive threshold.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 30‐day mortality 5 2683 Risk Ratio (M‐H, Fixed, 95% CI) 0.92 [0.67, 1.26]
2 60‐day mortality 3 2283 Risk Ratio (M‐H, Fixed, 95% CI) 1.08 [0.80, 1.44]
3 Longer‐term mortality: at 90, 120 and 365 days 2   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
3.1 90‐day mortality 2 484 Risk Ratio (M‐H, Fixed, 95% CI) 0.80 [0.55, 1.16]
3.2 120‐day mortality 1 200 Risk Ratio (M‐H, Fixed, 95% CI) 1.18 [0.56, 2.51]
3.3 365‐day mortality 1 200 Risk Ratio (M‐H, Fixed, 95% CI) 1.04 [0.65, 1.65]
4 Inability to walk 10 feet (3 m; or across a room) without human assistance 2   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
4.1 At 30 days 1 1995 Risk Ratio (M‐H, Fixed, 95% CI) 0.93 [0.84, 1.03]
4.2 At 60 days 2 2083 Risk Ratio (M‐H, Fixed, 95% CI) 1.00 [0.87, 1.15]
5 Regaining functional independence during hospitalisation 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6 Poor mobility/physical ability (at 10 days) 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
6.1 Unable to walk (CAS) 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
6.2 Bedridden (CAS) 1   Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
7 Mean change in mobility scores (score 0 to 9: best mobility) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
8 Thromboembolism (in hospital) 4 2416 Risk Ratio (M‐H, Fixed, 95% CI) 1.15 [0.56, 2.37]
9 Stroke (inpatient) 4 2416 Risk Ratio (M‐H, Fixed, 95% CI) 2.40 [0.85, 6.79]
10 Wound infection (in hospital) 3 2332 Risk Ratio (M‐H, Fixed, 95% CI) 1.61 [0.77, 3.35]
11 Cardiovascular events 4   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
11.1 Myocardial infarction 3 2217 Risk Ratio (M‐H, Fixed, 95% CI) 0.59 [0.36, 0.96]
11.2 Congestive heart failure (new diagnosis) 3 2332 Risk Ratio (M‐H, Fixed, 95% CI) 0.77 [0.48, 1.23]
12 Respiratory infections (namely pneumonia) 4 2416 Risk Ratio (M‐H, Fixed, 95% CI) 1.35 [0.95, 1.92]
13 Lower Extremity Physical Activities of Daily Living (ADL) (0 to 11: total dependency) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
13.1 30 days 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
13.2 60 days 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
14 Instrumental Activities of Daily Living (ADL) (higher scores = higher dependency) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
14.1 30 days 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
14.2 60 days 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
15 FACIT‐Fatigue score (higher scores = more energy) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
15.1 30 days 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
15.2 60 days 1   Mean Difference (IV, Fixed, 95% CI) 0.0 [0.0, 0.0]
16 Dependency (based on Modified Barthel Index) at 10 days 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
16.1 Substantially or completely dependent 1 284 Risk Ratio (M‐H, Fixed, 95% CI) 1.05 [0.92, 1.20]
16.2 Completely dependent 1 284 Risk Ratio (M‐H, Fixed, 95% CI) 0.94 [0.69, 1.27]
17 Length of stay in hospital (days) 4   Mean Difference (IV, Fixed, 95% CI) Subtotals only
17.1 USA 2 1304 Mean Difference (IV, Fixed, 95% CI) ‐0.27 [‐0.66, 0.12]
17.2 Canada 1 791 Mean Difference (IV, Fixed, 95% CI) ‐0.67 [‐1.98, 0.64]
17.3 Denmark 1 107 Mean Difference (IV, Fixed, 95% CI) 1.80 [‐3.23, 6.83]
17.4 UK 1 200 Mean Difference (IV, Fixed, 95% CI) ‐1.50 [‐7.81, 4.81]