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. 2015 Apr 21;2015(4):CD009699. doi: 10.1002/14651858.CD009699.pub2

ChiCTR‐TRC‐10000822.

Methods Randomised controlled trial
Participants Older people undergoing orthopaedic surgery who meet the following criteria:
  • American Society of Anesthesiologists classification 1‐2

  • good general condition

  • Hct > 0.35

  • platelet count > 100 g/L with normal function

  • normal coagulation

  • no serious functional organ diseases (heart, liver, lung and kidney)

  • no infectious fever or bacteraemia

  • no haematopoietic system diseases

Interventions Group 1:
  • transfusion if Hct < 0.25 and maintain Hct 0.25‐0.30


Group 2:
  • transfusion if Hct < 0.25 and continue transfusion even if Hct ≥ 0.30


Group 3:
  • Hct never decrease to 0.30, transfusion


Group 4:
  • Hct never decrease to 0.30, no transfusion


Group 5:
  • transfusion if Hct < 0.35 and maintain Hct > 0.35

Outcomes
  • Haemoglobin

  • Central venous pressure

  • Blood pressure (mean arterial pressure)

  • Oxygen saturation (SpO2)

  • Electrocardiograph

  • Airway pressure

  • Infusion volume

  • End tidal carbon dioxide (ETCO2) recovery

  • 24‐hour drainage

  • Heal of the incision

  • Infection

  • Hospital length of stay

  • Cognitive function

  • Complications (coagulation disorders, electrolytes disorders)

  • Haematocrit

Notes The trial was identified on the Chinese Clinical Trial Registry, but the record has not been updated since first added in 2010. We have been unable to find contact details for the named applicant (checked again 14 March 2013). The trial record states that the trial is due to close by 1 May 2015

Hct: haematocrit.