Table 2.

Highlighted Outcomes From GAP70+, GAIN, and INTEGRATE

Empty Cell	GAP70+	GAIN	INTEGERATE
Age	≥ 70 Mean 77.2 (70–96)	≥ 65 Median 71 (65–91)	≥ 70 Median 75.5 (72–79)
Number of patients	718	605	154
Diagnosis of GI malignancy	246 (34%)	202 (33%)	44 (29%)
Primary endpoint	Any Grade 3–5 toxicity	Any Grade 3–5 toxicity	HRQOL
Endpoint result	GAP70+ arm 50.7% Standart arm 71%	GAIN arm 50.5% Standart arm 60.6%	ELFI index change INTERGERATE arm −6.9 Standart arm −12.5
Overall Survival	GAP70+ arm 71.6% Standard arm 74.5% P:.38	Gain arm 66% Standard arm 64% P:.55	INTERGERATE arm 68.9% Standard arm 59% P:.79

Abbreviations; ELFI = Elderly Functional Index, GI =Gastrointestinal; GAIN = Geriatric assessment-driven intervention, HRQOL = Health-Related Quality of Life; GAP70+ = Geriatric Assessment for Patients 70 years and older; INTEGRATE = Integrated Geriatric Assessment and Treatment Effectiveness.