Skip to main content
. Author manuscript; available in PMC: 2024 Jul 1.
Published in final edited form as: Nature. 2023 Dec 13;625(7996):805–812. doi: 10.1038/s41586-023-06835-6

Extended Data Fig. 9 |. Cytotoxic function of base edited T cells in arrayed validation.

Extended Data Fig. 9 |

Cytotoxicity (measured by A375 target cell killing) of antigen-specific T cells base edited with control, positive (increased T cell activation, red), or negative (decreased T cell activation, blue) guides targeting selected genes measured with Incucyte live-cell imaging over time. n = 6 human donors, shown as mean (line) ± SE (shaded area).