Table 3.
Neuropsychological battery results for monolingual/bilingual speakers by clinical variant
| bvFTD | nfvPPA | svPPA | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||||
| Monolingual (N = 101) | Bilingual (N = 25) | p | N (mono/bi) | Monolingual (N = 55) | Bilingual (N = 22) | p | N (mono/bi) | Monolingual (N =66) | Bilingual (N = 30) | p | N (mono/bi) | |
| Age at Testing, mean (SD), y | 61.5 (10.0) | 65.6 (8.2) | 0.038 | - | 68.3 (7.5) | 67.5 (7.8) | 0.693 | - | 63.3 (6.0) | 65.7 (7.4) | 0.137 | - |
| MMSE (30) | 23.0 (7.2) | 23.9 (4.1) | 0.689 | 98/23 | 25.1 (4.7) | 25.3 (4.9) | 0.889 | 54/21 | 23.1 (6.3) | 21.7. (7.5) | 0.230 | 66/29 |
| GDS (30) | 6.9 (5.9) | 7.2 (7.6) | 0.544 | 78/19 | 8.7 (6.9) | 6.9 (5.2) | 0.377 | 46/18 | 8.4 (6.2) | 10.5 (8.2) | 0.143 | 52/25 |
| Episodic Memory | ||||||||||||
| CVLT Trials 1–4 (36) | 19.2 (8.1) | 16.8 (6.7) | 0.131 | 85/23 | 21.7 (6.2) | 21.1 (6.7) | 0.752 | 45/20 | 15.8 (7.3) | 16.2 (6.7) | 0.912 | 57/25 |
| CVLT 10 min (9) | 3.3 (2.8) | 2.5 (2.3) | 0.193 | 83/23 | 5.6 (2.3) | 5.2 (2.8) | 0.812 | 45/20 | 1.9 (2.4) | 1.6 (2.5) | 0.367 | 57/25 |
| Rey recall (17) | 7.0 (4.6) | 5.4 (4.0) | 0.137 | 95/24 | 10.0 (3.6) | 9.9 (3.0) | 0.854 | 53/21 | 6.3 (4.5) | 6.9 (4.5) | 0.499 | 62/30 |
| Speech and Language | ||||||||||||
| Sentence repetition (5) | 4.3 (1.0) | 3.5 (1.5) | 0.003 | 86/20 | 2.7 (1.5) | 3.0 (1.9) | 0.919 | 46/20 | 3.6 (1.4) | 3.5 (1.4) | 0.686 | 54/27 |
| Animal fluency | 10.9 (6.8) | 8.6 (4.3) | 0.112 | 90/22 | 11.6 (7.0) | 10.2 (6.0) | 0.287 | 51/21 | 7.7 (4.6) | 10.5 (8.2) | 0.082 | 62/26 |
| BNT (15) | 12.4 (3.9) | 9.3 (3.7) | <.001 | 91/23 | 12.3 (2.9) | 11.7 (3.6) | 0.292 | 55/21 | 4.7 (3.7) | 5.3 (4.4) | 0.919 | 62/28 |
| Sentence comprehension (5) | 3.8 (1.5) | 3.8 (1.1) | 0.646 | 84/20 | 3.9 (1.1) | 4.3 (1.0) | 0.223 | 46/20 | 4.5 (1.0) | 4.0 (1.2) | 0.049 | 52/27 |
| Verbal agility (6) | 5.0 (1.6) | 5.1 (1.3) | 0.695 | 80/20 | 2.5 (1.5) | 2.9 (1.6) | 0.716 | 44/20 | 5.1 (1.3) | 5.2 (0.9) | 0.873 | 50/27 |
| PPVT (16) | 13.8 (3.1) | 11.8 (3.3) | 0.004 | 81/17 | 14.4 (1.8) | 14.1 (2.6) | 0.396 | 48/20 | 8.2 (3.9) | 9.1 (4.6) | 0.730 | 51/24 |
| Irregular word reading (6) | 5.6 (1.2) | 5.0 (1.8) | 0.012 | 83/20 | 5.5 (0.7) | 5.1 (1.5) | 0.115 | 43/19 | 4.5 (1.4) | 4.6 (1.3) | 0.796 | 50/26 |
| Visuospatial | ||||||||||||
| VOSP (10) | 8.3 (1.9) | 7.6 (1.7) | 0.055 | 84/22 | 8.7 (1.5) | 7.8 (2.3) | 0.041 | 52/19 | 9.0 (1.7) | 8.8 (1.6) | 0.763 | 55/29 |
| Rey copy (17) | 13.9 (3.0) | 14.8 (1.5) | 0.231 | 95/24 | 14.4 (2.3) | 14.1 (2.4) | 0.486 | 54/20 | 15.3 (1.5) | 15.5 (0.9) | 0.741 | 64/30 |
| Calculations (5) | 3.7 (1.4) | 4.0 (1.1) | 0.433 | 95/23 | 4.1 (1.3) | 4.0 (1.0) | 0.502 | 55/21 | 4.2 (1.3) | 4.4 (0.6) | 0.672 | 65/28 |
| Frontal/Executive | ||||||||||||
| Digits Forward | 5.8 (1.5) | 5.4 (1.0) | 0.219 | 73/18 | 5.1 (1.4) | 5.2 (1.5) | 0.928 | 39/19 | 6.2 (1.5) | 6.6 (1.9) | 0.656 | 38/23 |
| Digits Backward | 3.6 (1.5) | 3.8 (1.3) | 0.662 | 73/24 | 3.2 (1.4) | 3.7 (1.2) | 0.181 | 51/21 | 4.8 (1.5) | 5.0 (1.5) | 0.726 | 63/27 |
| D words | 7.3 (4.7) | 7.2 (4.7) | 0.481 | 88/22 | 6.0 (4.2) | 5.0 (2.8) | 0.221 | 51/21 | 7.4 (4.5) | 7.5 (4.9) | 0.816 | 62/27 |
| Trails (lines/sec) | 0.3 (0.2) | 0.2 (0.2) | 0.211 | 78/22 | 0.2 (0.2) | 0.3 (0.2) | 0.518 | 50/20 | 0.3 (0.2) | 0.4 (0.3) | 0.279 | 57/25 |
| Design Fluency | 5.3 (3.9) | 5.2 (3.2) | 0.572 | 85/23 | 5.6 (2.9) | 7.2 (3.8) | 0.105 | 52/21 | 7.3 (3.5) | 7.5 (3.6) | 0.889 | 52/26 |
| Stroop color naming | 61.2 (22.0) | 55.3 (20.3) | 0.265 | 69/17 | 42.8 (16.9) | 39.8 (21.1) | 0.579 | 41/16 | 68.2 (19.2) | 62.8 (28.3) | 0.171 | 37/23 |
| Stroop inhibition | 31.9 (18.4) | 25.6 (15.6) | 0.175 | 75/19 | 24.8 (13.5) | 23.1 (12.3) | 0.496 | 44/16 | 37.1 (13.8) | 35.8 (20.5) | 0.605 | 50/24 |
| Abstraction (6) | 1.9 (1.4) | 2.3 (1.8) | 0.658 | 61/11 | 2.9 (1.6) | 3.1 (1.6) | 0.971 | 37/13 | 1.9 (1.3) | 1.9 (1.8) | 0.652 | 44/15 |
Abbreviations: BNT = Boston Naming Test, CVLT = California Verbal Learning Test, GDS = Geriatric Depression Scale, MMSE = Mini-Mental State Examination, PPVT = Peabody Picture Vocabulary Test, VOSP = Visual Object and Space Perception battery, mono = monolingual, bi = bilingual.
Note. Results derived from ANCOVAs (covariates = age and education). Red denotes significance with Bonferroni correction applied within each cognitive domain. These measures are derived from a neuropsychological battery described further in Kramer, et al..35