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. Author manuscript; available in PMC: 2025 May 1.
Published in final edited form as: Cytotherapy. 2024 Feb 17;26(5):498–505. doi: 10.1016/j.jcyt.2024.01.008

Figure 2. BM-MSC populations exhibit discordant transcriptomes.

Figure 2.

a, Heat map showing cluster analysis of the top 1000 most abundant transcripts in S (Lin−LEPR+) and ID and Ex (Lin−Sca1+) BM-MSCs. Color scale corresponds to per-gene z-score computed across each row. b, PCA analysis of data from (a). c, Genes contributing to PC1 and PC2. Y-axis represents the percent contribution to the corresponding principal component. d-g, Volcano (d, f) and violin (e, g) plots of DEGs in ID vs. S (d, e) and Ex vs ID (f, g) BM-MSCs. h & i, Top GO terms (biological processes) based on p-value identified by GSEA of DEGs for ID vs. S (h) and Ex vs. ID BM-MSCs (i). Arrows indicate gene sets corresponding to each GO term that show positive (up) or negative (down) enrichment.