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. Author manuscript; available in PMC: 2025 May 1.
Published in final edited form as: Cytotherapy. 2024 Feb 17;26(5):498–505. doi: 10.1016/j.jcyt.2024.01.008

Figure 3. Isolation status-resolved changes in the BM-MSC transcriptome in pseudotime.

Figure 3.

a, Plot of within sum of squares from K-means clustering of RNA-seq data from S, ID, and Ex BM-MSCs depicting the variance within the clusters. b, Gene expression patterns identified for the 5 most significant clusters from (a) displayed in pseudotime. c-g, Transcript profiles (left panel) for each cluster depicted in (b). Color scale corresponds to the fitness score for each gene to the cluster centroid line (black). Dot plot showing biological process GO terms generated by gene enrichment corresponding to each cluster (right panel).