Table 1.
Peng et al | Steele et al | Lin et al | Elyada et al | Moncada et al | Bernard et al | |
---|---|---|---|---|---|---|
Year of publication | 2019 | 2020 | 2020 | 2019 | 2020 | 2019 |
Country of enrollment | China | USA | South Korea, USA | USA | USA | USA |
PDAC pancreas tissue samples | ||||||
Treatment-naïve, % | 100% | 100% | 100% | 100% | 100% | 100% |
Patients, N | 24 | 16 | 10 | 6 | 3 | 2 |
Sex, N | ||||||
Female | 13 | 6 | 4 | 2 | Unknown | 0 |
Male | 11 | 10 | 6 | 4 | Unknown | 2 |
Age, years median (range) | 59 (36–72) | 66 (42–80) | 66 (41–80) | 73 (64–87) | Unknown | 61 (59–62) |
Diabetes, N | 10 | 6 | Unknown | Unknown | Unknown | Unknown |
Staging, N | ||||||
Localized | 24 | 12 | 10 | 5 | Unknown | 1 |
Metastatic | 0 | 4 | 0 | 1 | Unknown | 1 |
Grading, N | ||||||
Well differentiated | 3 | Unknown | 0 | 0 | Unknown | 0 |
Moderately differentiated | 8 | ≥6 | 6 | 3 | Unknown | 0 |
Poorly differentiated | 13 | Unknown | 2 | 3 | Unknown | 2 |
Anaplastic | 0 | Unknown | 2 | 0 | Unknown | 0 |
Tumor location, N | ||||||
Head or uncinate | 15 | Unknown | Unknown | Unknown | Unknown | 1 |
Neck, body or tail | 9 | Unknown | Unknown | Unknown | Unknown | 1 |
Specimen, N | ||||||
Surgery (resected) | 24 | 6 | 10 | 6 | 3 | 2 |
Biopsy (FNA) | 0 | 10 | 0 | 0 | 0 | 0 |
Survival | Unknown | Unknown | Unknown | Unknown | Unknown | Unknown |
Non-malignant pancreas tissue samples | ||||||
Patients, N | 11 | 3 | 0 | 2 | 0 | 0 |
Sex, N | ||||||
Female | 6 | 2 | --- | 1 | --- | --- |
Male | 5 | 1 | --- | 1 | --- | --- |
Histology, N | ||||||
Normal | 10 | 1 | --- | 0 | --- | --- |
Normal-adjacent to adenocarcinoma | 1 | 2 | --- | 2 | --- | --- |
Specimen, N | ||||||
Surgery (resected) | 11 | 3 | --- | 2 | --- | --- |
Biopsy (EUS-FNA) | 0 | 0 | --- | 0 | --- | --- |
PDAC, pancreatic ductal adenocarcinoma
EUS-FNA, endoscopic ultrasound guided-fine needle aspiration