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. 2024 Apr 19;15:1360132. doi: 10.3389/fimmu.2024.1360132

Table 2.

SNPs used in MR analysis of the association between the two gut microbiota and spinal stenosis.

Bacterial taxa (exposure) SNP Effect allele Other allele Exposure (Bacteria) Outcome (spinal stenosis) F-statistic
Beta SE P-value Beta SE P-value
Eubacterium fissicatena group rs10147907 T G 0.17 0.04 1.36E-05 0.05 0.02 0.04 18.92
rs11818408 G A 0.11 0.02 8.04E-06 0.01 0.01 0.55 19.93
rs11876297 T C 0.13 0.03 3.06E-06 0.00 0.01 0.89 21.78
rs151257695 A G 0.21 0.05 4.10E-06 0.03 0.02 0.14 21.21
rs1768152 T C 0.14 0.03 1.03E-05 0.03 0.02 0.11 19.46
rs2733072 G A 0.11 0.02 1.57E-06 0.01 0.01 0.56 23.06
rs3771393 C T 0.13 0.03 9.27E-07 0.00 0.01 0.87 24.07
rs6934739 A G 0.11 0.03 1.04E-05 0.01 0.01 0.31 19.44
rs7104872 G A 0.14 0.03 2.05E-06 -0.01 0.02 0.75 22.54
Oxalobacter rs11108500 A G -0.20 0.04 3.17E-06 -0.06 0.02 0.00 21.70
rs111966731 T C 0.21 0.05 6.22E-06 0.01 0.02 0.50 20.42
rs12002250 A C 0.22 0.05 3.22E-06 -0.02 0.03 0.46 21.68
rs1569853 T C -0.14 0.03 3.33E-06 -0.04 0.02 0.04 21.61
rs36057338 G T 0.21 0.04 8.15E-07 0.01 0.03 0.69 24.32
rs3862635 C T -0.17 0.04 1.25E-05 -0.03 0.02 0.11 19.08
rs4428215 G A 0.13 0.02 7.50E-08 0.02 0.01 0.24 28.93
rs6000536 C T -0.13 0.03 2.45E-07 -0.01 0.02 0.50 26.63
rs6993398 G A 0.13 0.03 5.06E-06 0.00 0.02 0.87 20.81
rs736744 C T 0.12 0.02 2.41E-08 0.02 0.01 0.11 31.13
rs115602804 G A 0.10 0.02 3.69E-06 0.00 0.02 0.91 21.41