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. 2024 May 2;7(5):e249298. doi: 10.1001/jamanetworkopen.2024.9298

Table 1. Baseline Patient Characteristics.

Characteristic Patients, No. (%) P value
All SMT (n = 111) EVT (n = 135)
Age, median (IQR), y 71 (63-78) 72 (65-78) 70 (59-77) .12
Sex
Female 118 (48.0) 52 (46.8) 66 (48.9) .08
Male 128 (52.0) 59 (53.2) 69 (51.1)
Medical history
Diabetes 42 (17.1) 20 (18.0) 22 (16.3) .72
Hypertension 151 (61.4) 75 (67.6) 76 (56.3) .07
Atrial fibrillation 117 (47.6) 57 (51.4) 60 (44.4) .28
Hyperlipidemia 43 (17.5) 16 (14.4) 27 (20.0) .25
Smoking 57 (23.2) 26 (23.4) 31 (23.0) .93
Clinical characteristics
Blood pressure, median (IQR), mm Hg
Systolic 150 (133-170) 154 (134-180) 147 (130-164) .006
Diastolic 87 (76-100) 88 (77-102) 85 (73-100) .24
Hemisphere
Left 118 (48) 56 (50.5) 62 (45.9) .48
Right 128 (52) 55 (49.5) 73 (54.1)
Glucose, median (IQR), mmol/La 7.2 (6.1-8.7) 7.1 (6.0-8.6) 7.2 (6.2-8.9) .39
IVT 62 (25.2) 30 (27.0) 32 (23.7) .55
General anesthesia NA NA 23 (17.0) NA
NIHSS score, median (IQR) 18 (15-23) 18 (14-25) 18 (15-22) .98
ASPECTS
0-1 157 (63.8) 83 (74.8) 74 (54.8) .001
2 89 (36.2) 28 (25.2) 61 (45.2)
Onset to imaging time, median (IQR), minb 305 (162.5-504.0) 314 (168.5-611.3) 295 (152.0-455.0) .18
Onset to puncture time, median (IQR), minc NA NA 353.5 (234.5-535.8) NA
Onset to recanalization time, median (IQR), mind NA NA 439.5 (323.8-615.0) NA
Occlusion site
Intracranial internal carotid artery 120 (48.8) 41 (36.9) 79 (58.5) <.001
M1 middle cerebral artery segment 111 (45.1) 67 (60.4) 44 (32.6)
M2 middle cerebral artery segment 15 (6.1) 3 (2.7) 12 (8.9)
Stroke causative mechanism
LAA 77 (31.3) 41 (36.9) 36 (26.7) .24
Cardioembolism 137 (55.7) 58 (52.3) 79 (58.5)
Other 9 (3.7) 2 (1.8) 7 (5.2)
Unknown 23 (9.3) 10 (9.0) 13 (9.6)
Successful recanalization (mTICI ≥2b) NA NA 110 (81.5) NA

Abbreviations: ASPECTS, Alberta Stroke Program Early Computed Tomography Score; EVT, endovascular treatment; IVT, intravenous thrombolysis; LAA, large artery atherosclerosis; mTICI, modified Thrombolysis In Cerebral Infarction score; NIHSS, National Institutes of Health Stroke Scale; SMT, standard medical treatment.

a

Data on glucose were missing for 4 patients in the EVT group and 3 patients in the SMT group.

b

Data on onset to imaging were missing for 5 patients in the SMT group.

c

Data on onset to puncture were missing for 1 patient in the EVT group.

d

Data on onset to recanalization were missing for 1 patient in the EVT group.