Table 3.

Parkinson disease genes predicted by a graph-augmented random forest model to also be associated with Alzheimer disease.

Gene symbol	Gene name	Notes (from the Entrez Gene summary)
ATXN2	Ataxin-2	Modulates endocytosis, ribosomal translation, and mitochondrial function; aberrations are linked to diverse neurodegenerative diseases, diabetes, and obesity
CHRNB1	Cholinergic receptor nicotinic β1 subunit	Beta subunit of muscle acetylcholine receptor involved in transmitting signals at neuromuscular junction
DCTN1	Dynactin subunit 1	Dynactin is a macromolecular complex involved in many cellular functions, including the formation of neuronal pathways
FYN	FYN proto-oncogene, Src tyrosine kinase family	Membrane-associated tyrosine kinase involved in control of cell growth; highly expressed in brain tissue
KCNIP3	Potassium voltage-gated channel interacting protein 3	Voltage-gated potassium channel–interacting protein that is critical to neuronal excitability