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AFM images (A) of S100A8, S100A9, and CP after 65 h of aggregation at 37 °C (scale bar, 500 nm). Aggregates height distribution (B) with box plots indicating the interquartile range and error bars are for one standard deviation (sample size, 50). Fluorescence microscopy images (C) of S100A8, S100A9, CP aggregates, and buffer stained with ThS (scale bar, 10 μm). Transmission electron microscopy image (D) of S100A8 aggregates stained with uranyl acetate (scale bar, 500 nm).
