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. 2023 Aug 17;26(Suppl 2):S136–S154. doi: 10.1093/neuonc/noad144

Figure 2.

Figure 2.

Normal mitochondrial function in cells. ATP production in mitochondria is produced by a cascade of reaction including glycolysis, tricarboxylic acid (TCA) cycle, or electron transport chain (ETC). The ClpXP complex, comprised of ClpP and ClpX, degrades misfolded proteins in the mitochondria, to maintain its functional integrity.