Table 1.
Digital brain health monitoring platform: technology use and data description.
| Technology | Platform | Measures | Participant schedule | Assessment frequency | Compliance tracking | Data upload | |
|---|---|---|---|---|---|---|---|
| Active engagement application | Linus participant | Smartphone | Cognition, speech, gait and balance, questionnaires | Complete 25 min series of tasks once remotely | Quarterly | Daily | Automatic upload (w Internet) |
| Lumosity | Smartphone, computer | Cognition | Complete 5 tasks (15 min) remotely | Quarterly | Bi-weekly | Automatic upload (w Internet) | |
| Mezurio | Smartphone | Cognition, speech, motor function | Complete 10 min of tasks daily for 2 weeks remotely | Quarterly | Daily | Automatic upload (w Internet) | |
| Passive engagement application | Longevity | Smartphone | Motor function | Data collected continuously in the background | Continuousx | Weekly | Automatic upload (w Internet) |
| NeuraMetrix typing cadence application | Computer (PC Only) | Cognition, motor function | Data collected continuously in the background | Continuousx | Daily | Automatic upload (w Internet) | |
| Activity wearable | Fitbit charge 4 | Wrist-worn device, smartphone | Physical activity, heart rate, sleep | Wear wrist device day and night for 2 weeks | Quarterly | Daily | Automatic upload (w Internet and Bluetooth) |
| Wrist-worn wearable | Wrist-worn device | Physical activity, sleep | Wear wrist device day and night for 2 weeks | Quarterly | One time upload** | Manual upload by staff | |
| Sleep wearable | Dreem3 headband | Head-worn device, Smartphone | Sleep movement, respiration, EEG | Wear sleep headband for 3 or more nights | Quarterly | Daily | Automatic upload (w Internet) when charging |
| SleepImage | Finger-worn device, Smartphone, cloud-computing | ANS-based sleep evaluation, pulse oximetry, respiration, sleep | Wear sleep ring for 3 or more nights | Quarterly | Daily | Automatic Upload (w Internet and Bluetooth) | |
| Staff-guided technology | APDM mobility lab* | Wearable sensor system | Motion, gait and balance metrics | Complete set series of tasks in person | Annually | Not applicable | Staff guided after assessment |
| Linus tester* | Tablet | Digital pen movement, multi-domain cognition | Complete set series of tasks in person | Annually | Not applicable | Staff guided after assessment | |
| Digital voice recorder* | Voice recorder | Voice | Complete picture description and recall in person or remotely | Annually | Not applicable | Staff guided after assessment |
*
Device used during staff-guided assessments. Gait and balance sensors and tablet-based assessment are used only during in-clinic visits. Digital voice recorder is used during staff-guided in-clinic and remote visits.
**
The wristband continuously collects data from an embedded accelerometer after study staff links the device to a study-based smartphone. Then, the collected data is uploaded manually to an Amazon Web Services (AWS) backend when the technology is returned to the study site.
x
Continuous smartphone and computer tracking entails the capture of typing speed and usage data whenever a participant uses their personal device.