Table 4.

Phyllane A (76) and 12-methoxybarbatusol (77).

Cell lines (IC50, μM)[a]	77	Positive control
T. b. rhodesiense	45.8 (43.6, 48.0); 1.7[b]	0.04[c]
T. cruzi	111.5 (134.8, 88.2); 0.7[b]	5.7[d]
L. donovani	34.8 (17.8, 51.9); 2.3[b]	0.9[e]
P. falciparum	10.7 (9.8, 11.6); 7.4[b]	0.01[f]
L6 cells	79.4 (54.0, 104.8)	0.009[g]

^[a]Each value corresponds to the mean of two independent assays, with individual values indicated in parentheses.

^[b]Selectivity index,

^[c]Melarsoprol,

^[d]Benznidazole,

^[e]Miltefosine,

^[f]Chloroquine,

^[g]Phodophyllotoxin.