Table 6.
Amentonone (96) and brevitaxin (97) and their cytotoxicity against various cancer cell lines in vitro.
|
||||
|---|---|---|---|---|
| ED50 (μg/mL) | A-549 | Hep 3B | HT-29 | MCF-7 |
| 96 | 19.1±2.9 | 15±2.3 | ||
| 97 | 5.1±0.9 | 6.1±0.6 | 2.72±0.1 | 0.08±0.05 |
| 5-Fluorouracil | 3.1±0.2 | 0.6±0.3 | 0.6±0.1 | 1.5±0.1 |
5-Fluorouracil: positive control.