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. Author manuscript; available in PMC: 2024 May 3.
Published in final edited form as: Chem Biodivers. 2022 Nov 8;19(11):e202200793. doi: 10.1002/cbdv.202200793

Table 9.

Anticancer studies of synthetic icetexanes reported by Deng and coworkers.

IC50 (μM)[a] HCT-116 COLO-205 Caco-2
36 >20.87 >20.87 13.71±1.36
29 18.77±1.39 11.15±1.07 3.07±1.52
54 2.93±1.08 3.18±0.95 2.71±1.10
55 13.33±1.57 10.42±1.38 3.86±0.98
56 >20.23 >20.23 >20.23
58 10.58±2.01 7.81±1.74 7.20±1.56
190 18.55±2.33 18.52±2.52 10.42±2.64
191 11.07±1.92 7.52±1.19 13.81±1.82
193 2.70±0.73 3.39±1.45 2.69±1.08
5-FU [b] 7.38 + 0.83 5.29±0.32 7.77±1.24
[a]

5-Fluorouracil (5-FU): positive control.

[b]

An average of three determinations.