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. 2024 Apr 18;15:1380386. doi: 10.3389/fimmu.2024.1380386

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Copyright © 2024 Pernes, Alsayah, Tucci and Bashford-Rogers

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Boxplots of the variation of the proportion of multi-omics-defined B cell populations within flow-cytometric style gating between diseases for (A) naïve B cells and IgD- CD27- B cells (showing only those with statistical significance), and (B) the corresponding table of significance for all comparisons. Overall p-values of frequencies associating with disease status is provided only for combinations with >3 individuals with non-zero frequencies across each disease state, given at the top of each figure (by ANOVA) and p-values between disease states are provided (by Wilcoxon test using Holm multiple testing correction). Significant values (p-values<0.05) are highlighted in red. CC, Hospitalised COVID-19 (critical); CComm, Healthcare workers COVID-19 (convalescent); CM, COVID-19 (mild); CS, Hospitalised COVID-19 (severe); Flu, Influenza patients; HV, Healthy volunteers; Sepsis, Hospitalised sepsis.