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. 2024 Feb 24;103(5):103589. doi: 10.1016/j.psj.2024.103589

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© 2024 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

CYP21A1 promotes the synthesis of steroid hormones in chicken granulosa cells. Effects of interference and overexpression CYP21A1 on progesterone secretion by chicken ovarian granulosa cells (A, D). Effects of interference and overexpression CYP21A1 on estradiol secretion by chicken ovarian granulosa cells (B, E). Effects of interference and overexpression CYP21A1 on the mRNA expression of several key genes involved in steroid hormone synthesis (C, F). Data are presented as mean ± SEM. *P < 0.05, **P < 0.01.