Table 3.

Safety analysis.

	All grade		Grade 3 or higher
	Number of cases	%	Number of cases	%
N	43
All adverse events	38	88.4	18	41.9
Neutropenia	13	30.2	8	18.6
Stomatitis	5	11.6	0	0.0
Thrombocytopenia	5	11.6	0	0.0
Interstitial lung disease	4	9.3	3	7.0
Leg edema	4	9.3	0	0.0
Paronychia	3	4.7	1	2.3
Febrile neutropenia	2	4.7	2	4.7
Intracranial hemorrhage	2	4.7	2	4.7
AST ALT increased	2	4.7	1	2.3
Hypertension	2	4.7	0	0.0
Nausea	2	4.7	0	0.0
Proteinuria	2	4.7	0	0.0
Dysgeusia	2	4.7	0	0.0
Alopecia	2	4.7	0	0.0
Peripheral neuropathy	2	4.7	0	0.0
Pneumothorax	1	2.3	1	2.3
General edema	1	2.3	1	2.3
Hyponatraemia	1	2.3	1	2.3
Fracture	1	2.3	1	2.3
Anorexia	1	2.3	1	2.3
Malaise	1	2.3	1	2.3
Gastrointestinal hemorrhage	1	2.3	1	2.3
Epistaxis	1	2.3	0	0.0
Anaemia	1	2.3	0	0.0
Bloody stools	1	2.3	0	0.0
Constipation	1	2.3	0	0.0
Dyspnoea	1	2.3	0	0.0