Skip to main content
. Author manuscript; available in PMC: 2024 May 3.
Published in final edited form as: Ann Surg. 2019 Jul;270(1):12–20. doi: 10.1097/SLA.0000000000003201

Table 3:

Comparison of fluorescence at resection margin and margin pathology for patients with invasive malignancies.

Following Neoadjuvant Treatment

# Procedure Neoadjuvant Treatment CA19–9 Response* Tumor Regression on Cross Sectional Imaging Final Pathology TBR Neck Margin Fluorescence Retroperitoneal Margin Fluorescence Frozen Section Diagnosis Final Margin Status
1 PD None -- -- PDAC 7.71 Yes No N/A (+) neck, (−) uncinate
2 DP None -- -- PDAC 3.77 Yes No N/A (+) neck
3 PD None -- -- Intrapancreatic cholangiocarcinoma 2.08 Yes No (+)
adenocarcinoma
(−)
4 DP None -- -- PDAC 12.43 No No N/A (−)
5 PD None -- -- PDAC 2.13 No No (−) (−)
7 PD None -- -- PDAC 3.29 Yes No N/A (+) neck, (−) uncinate
10 DP CRT Yes Yes PDAC, 10% viable tumor 1.25 No No N/A (−)
11 DP No -- -- 4.20 No No (−) (−)
13 DP CO Yes No PDAC, 100% viable tumor 4.63 No No N/A (−)
13 PD CO Yes No PDAC, 100% viable tumor 2.76 Yes No N/A (+) neck, (−) uncinate
16 DP CRT Yes Yes PDAC, 100% viable tumor 4.83 Yes No N/A (+) neck
17 PD No -- -- PDAC 3.38 No No (+) HGD (−)
19 PD CO No No PDAC, 100% viable tumor 5.06 Yes No (−) (−)

* >50% reduction in CA19–9 immediately prior to surgery

Abbreviations: TBR tumor-to-background ratio, PD pancreaticoduodenectomy, PDAC pancreatic ductal adenocarcinoma, DP distal pancreatectomy, CRT chemoradiotherapy, CO chemotherapy only, HGD high grade dysplasia.