Figure 4.

Partial suppression of IGF1R activity attenuates in vitro doxorubicin and cadmium chloride -induced podocyte death

(A) Fold change in cell survival of NC-IGF1RKO relative to non-transduced control after 24-h exposure to 250 ng/mL doxorubicin and P-IGF1RKD compared to wild-type podocytes after 24-h exposure to 250 ng/mL doxorubicin, 50 μM CdCl₂ or 5 ng/mL LPS. Data are expressed as mean ± SEM, t-test, ∗p < 0.05, ∗∗p < 0.005, ∗∗∗∗p < 0.0001. n = 3–4 independent experiments.

See also Figure S6.