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. 2024 Mar 6;9(5):1284–1297. doi: 10.1016/j.ekir.2024.02.1431

Table 4.

Univariable and multivariable logistic regression of the predictive factors for transient dialysis (n = 71)

Factors Univariable Analysis
Multivariable Analysis (adjusted to PLEX)
OR 95% CI P-value OR 95% CI P-value
Age ˂ 60 yr 0.933 0.336–2.591 0.895
Male 1.034 0.375–2.853 0.948
GPA 2.700 1.004–7.260 0.049a
PR3 2.456 0.917–6.579 0.074
Alveolar hemorrhage 1.004 0.351–2.868 0.994
Hb at diagnosis ---- 1.432 1.014–2.024 0.042a
Erythrocyte sedimentation rate at diagnosis 1.013 0.995–1.031 0.171
SCr at diagnosis 0.800 0.669–0.956 0.014a
eGFR at diagnosis 1.069 1.001–1.141 0.046a
MCCS
 Minimal 8.039 1.965–32.884 0.004a 6.138 1.389–27.118 0.017a
 Mild 1.137 0.419–3.089 0.801
 Moderate 0.500 0.167–1.496 0.215
 Severe 0.131 0.016–1.087 0.060
 MCCS score 0.728 0.593–0.893 0.002a
Berden
 Focal 6.875 1.906–24.798 0.003a 5.017 1.287–19.567 0.020a
 Crescentic 1.329 0.494–3.573 0.573
 Mixed 0.276 0.081–0.938 0.039a
 Sclerotic 0.203 0.024–1.753 0.147
Intervention
 Remission-induction treatment
 Rituximab (vs. CYC) ---- 1.335 0.497–3.587 0.567
Remission-induction adjuvant therapies
 Plasma exchange 1.745 0.661–4.606 0.261 1.650 0.548–4.965 0.373
 i.v. methylprednisolone 1.603 0.288–8.905 0.590

CI, confidence interval; CYC, Cyclophosphamide; eGFR, estimated glomerular filtration rate; Hb, hemoglobin; GPA, granulomatosis with polyangiitis; MCCS, Mayo Clinic Chronicity score; OR, odds ratio; PLEX, plasma exchange; PR3, proteinase 3; Scr, serum creatinine.

a

P ≤ 0.05, indicate statistical significance.