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. Author manuscript; available in PMC: 2024 May 4.
Published in final edited form as: Acta Biomater. 2022 Mar 9;143:63–71. doi: 10.1016/j.actbio.2022.03.006

Figure 6 |. Effect of Hydrogel Stiffness and Viscoelasticity on Tendon Cell Shape.

Figure 6 |

The effect of alginate hydrogel modulus and stress relaxation on cell shape were evaluated and quantified during aging using (a) confocal imaging and (b) image analysis. Cells were stained with phalloidin (green, F-actin) and DAPI (blue, nuclei). *P < 0.0125 indicates significant differences, as analyzed by two-way ANOVAs with post hoc tests with Bonferroni corrections. Data shown as violin plots with median and IQR in dashed lines. N=240cells/group. Scale bar: 100μm; Inset scale bar: 20μm.