Table 1.

The selected CTL epitopes for the final vaccine construction are provided by the NetCTL and IEDB servers.

Proteins/epitopes (position)	Supertypes/HLA class I alleles	Immunogenicity score	Antigenicity/allergenicity	Toxicity	Epitope conservation (%)	Homology to human proteins
Spike/WTAGAAAY (258–266)	A1, A26, B58, B62/ HLA-A*68:23, HLA-B*15:17, HLA-C*03:03, HLA-A*26:02, HLA-A*29:02, HLA-A*32:15, HLA-B*40:13, HLA-C*12:03, HLA-A*30:02, HLA-B*15:02, HLA-A*26:01, HLA-A*32:07, HLA-B*35:01,HLA-B*27:20, HLA-A*68:01, HLA-C*14:02	0.1525	0.6306 (antigen)/non-allergen	Non-toxin	100%	Non-homolog
Spike/KVGGNYNYR (442–450)	A3/ HLA-A*68:23, HLA-A*31:01, HLA-A*32:07, HLA-A*02:50, HLA-C*12:03, HLA-B*27:20, HLA-B*40:13, HLA-A*32:15, HLA-C*03:03	0.0277	1.5212 (antigen)/non-allergen	Non-toxin	100	Non-homolog
Spike/RSYSFRPTY (490–498)	A1, A3, B27, B58, B62/ HLA-B*15:17, HLA-B*15:03, HLA-A*32:07, HLA-C*12:03, HLA-C*03:03, HLA-A*68:23, HLA-B*27:20, HLA-B*40:13, HLA-A*30:02, HLA-A*32:01, HLA-B*58:01, HLA-A*30:01, HLA-B*15:01, HLA-A*02:17, HLA-C*07:02	0.0083	0.9553 (antigen)/non-allergen	Non-toxin	100	Non-homolog
Nucleocapsid/KTFPPTEPK (361–369)	A3/ HLA-A*11:01, HLA-A*68:23, HLA-A*30:01, HLA-B*27:20, HLA-C*12:03, HLA-B*40:13, HLA-A*32:07, HLA-C*14:02, HLA-A*03:01, HLA-A*31:01, HLA-A*68:01, HLA-C*03:03, HLA-A*32:01	0.1306	0.9553 (antigen)/non-allergen	Non-toxin	100%	Non-homolog
Membrane/ITVATSRTL (168–176)	B62/ HLA-C*03:03, HLA-A*68:23, HLA-B*15:17, HLA-A*32:07, HLA-A*02:50, HLA-C*15:02, HLA-B*15:02, HLA-C*12:03, HLA-B*27:20, HLA-A*02:17, HLA-C*14:02, HLA-B*40:13, HLA-A*02:11	0.1306	0.7571 (antigen)/non-allergen	Non-toxin	100%	Non-homolog
Envelope/TLAILTALR (30–38)	A3/ HLA-B*27:20, HLA-A*68:01, HLA-A*32:07, HLA-A*02:50, HLA-A*68:23, HLA-A*31:01, HLA-C*12:03, HLA-A*32:15, HLA-C*03:03, HLA-A*33:01, HLA-B*40:13	0.1989	0.7223 (antigen)/non-allergen	Non-toxin	100%	Non-homolog