. 2024 Apr 4;16(4):e57580. doi: 10.7759/cureus.57580

Table 8. Correlations between GTV and the marginal doses relative to each prescribed dose in four different dose prescriptions.

The correlations between the GTVs and the marginal dose metrics (%) relative to the prescribed dose (100%) are shown as the results of SRCC

PD: prescribed dose; GTV: gross tumor volume; D_{V-0.01 cc}: a minimum dose to cover a target volume minus 0.01 cc; GTV + X mm: GTV evenly expanded by X mm; D_X%: a minimum dose covering at least X% of a target volume; NS: not significant

Dose prescription	Dose metrics	Relative dose (range, %) to PD	Spearman’s rho	P value
GTV D_98%	GTV D_{V-0.01 cc}	95.4-98.8	-0.937	0.002**
	GTV + 1 mm D_{V-0.01 cc}	78.9-84.5	0.786	0.036*
	GTV + 2 mm D_{V-0.01 cc}	62.4-71.9	0.893	0.007**
GTV D_{V-0.01 cc}	GTV D_98%	101.2-104.9	0.937	0.002**
	GTV + 1 mm D_{V-0.01 cc}	79.8-88.2	0.786	0.036*
	GTV + 2 mm D_{V-0.01 cc}	63.1-75.2	0.929	0.003**
GTV + 1 mm D_95%	GTV D_{V-0.01 cc}	100.8-109.1	-0.901	0.006**
	GTV + 1 mm D_{V-0.01 cc}	85.8-94.1	0.750	0.052 (NS)
	GTV + 2 mm D_{V-0.01 cc}	68.8-81.6	0.893	0.007**
GTV + 2 mm D_95%	GTV D_{V-0.01 cc}	113.3-130.7	-0.883	0.009**
	GTV + 1 mm D_{V-0.01 cc}	102.3-113.6	-0.685	0.090 (NS)
	GTV + 2 mm D_{V-0.01 cc}	89.0-94.8	-0.523	0.229 (NS)