Table 9. Correlations between GTV and the GTV DV-0.01 cc in three specific dose prescriptions based on BED.
The specific dose prescriptions followed the 5-fraction examples shown in Table 4. The correlations between the GTV and the BED10 of GTV DV-0.01 cc are shown as the results of SRCC
GTV: gross tumor volume; GTV + X mm: GTV evenly expanded by X mm; DV-0.01 cc: a minimum dose to cover a target volume minus 0.01 cc; DX%: a minimum dose covering at least X% of a target volume; BED10: biologically effective dose based on the linear-quadratic model with an alpha/beta ratio of 10; SRCC: Spearman’s rank correlation coefficient
| Dose prescription | GTV DV-0.01 cc (range, BED10) | Spearman’s rho | P value |
| GTV D98% | 74.9-78.9 Gy | -0.890 | 0.007 ** |
| GTV + 1 mm D95% | 60.7-67.9 Gy | -0.901 | 0.006 ** |
| GTV + 2 mm D95% | 59.5-73.0 Gy | -0.964 | <0.001 *** |