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. 2024 May 5;15:63. doi: 10.1186/s40104-024-01021-8

Table 7.

Intestinal morphology and crypt cell proliferation of nursery pigs fed diets with increasing levels of xylanase and β-glucanase combination (XG)

Item  XG, (TXU/TGU)/kg SEMb  P value
0 280/125 560/250a 840/375 1,120/500 Linear Quadratic
Mid-jejunum
 Villus height, µm 492 553 525 515 535 26 0.572 0.530
 Crypt depth, µm 214 220 208 198 232 11 0.692 0.166
 VH:CDc 2.33 2.53 2.59 2.65 2.32 0.15 0.827 0.085
Ki-67+d, % 32.2 31.9 34.5 30.9 30.1 1.21 0.195 0.138

aAn observation of pigs fed a diet with 560/250 (TXU/TGU)/kg was removed from the data set for the final analysis as the observation confirmed as an outlier; experimental unit was a pig and each level had 8 replicates (totaling 40 observations)

bSEM Standard error of the means

cVH:CD Villus height to crypt depth ratio

dRatio of Ki-67 positive cell to total cell in the crypt, which represents crypt cell proliferation