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Transactivation by HNF-4A variant on HNF1A- and G6PC-linked reporter systems in transiently transfected (a and d) HK2, (b) MIN6, and (c) HepG2 cells transfection by WT or HNF4A variant plasmids together with (a–c) pGL3-HNF1A and (d) pGL3-G6PC reporter plasmids. Empty vector (EV) was used as a negative control. Each bar represents the mean of nine readings ± SD, taken from three parallel readings from each of three independent experimental days. *indicates P < 0.05.
