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. Author manuscript; available in PMC: 2025 May 1.
Published in final edited form as: J Allergy Clin Immunol. 2024 Feb 22;153(5):1381–1391.e6. doi: 10.1016/j.jaci.2024.01.026

Table 1.

Mast cell density (cells/mm2) by location and disease state


Control Remission Active p value
Epithelium 9 (mean) 22 124 p < 0.0001
10 (median) 8 104
0–25 (range) 1–155 9–409

n 21 20 36
Patients 20 20 34

Papillae 536 291 125 p < 0.0001
591 301 79
0–1,386 0–601 0–737

n 19 18 35
Patients 18 18 33

LP 123 68 49 p = 0.0069
81 59 33
22–269 33–132 6–294

n 6 14 20
Patients 5 14 18

Active, active eosinophilic esophagitis; Control, non-eosinophilic esophagitis; LP, lamina propria; n, number of biopsy sections; Remission, eosinophilic esophagitis in remission.

Kruskal-Wallis test used for calculation of p value.