Fig. 1.

Improvement in itch (observed case [OC]).^a a Worst Pruritus Numerical Rating Scale (WP-NRS) improvement ≥ 4.^b b WP-NRS 0/1.^c Error bars indicate 95% confidence interval. ^aAssessed daily through week 16, and reported as the weekly average; assessed at scheduled visits thereafter. ^bAssessed in patients with WP-NRS ≥ 4 at baseline. ^cAssessed in patients with WP-NRS > 1 at baseline. PBO placebo, UPA upadacitinib