Fig. 2.

Improvement in pain and other skin symptoms (observed case [OC]). a Atopic Dermatitis Symptom Scale (ADerm-SS) Skin Pain improvement ≥ 4.^a b Atopic Dermatitis Symptom Scale 7-item symptom score (ADerm-SS TSS-7) improvement ≥ 28.^b c Patient-Oriented Eczema Measure (POEM) improvement ≥ 4.^c d ADerm-SS Skin Pain 0/1.^d,e e ADerm-SS TSS-7 0–11.^f f POEM 0–2.^g Error bars indicate 95% confidence interval. ^aAssessed in patients with ADerm-SS Skin Pain ≥ 4 at baseline. ^bAssessed in patients with ADerm-SS TSS-7 ≥ 28 at baseline. ^cAssessed in patients with POEM ≥ 4 at baseline. ^dAssessed in patients with ADerm-SS Skin Pain ≥ 2 at baseline. ^eAssessed daily through week 16, and reported as the weekly average; assessed at scheduled visits thereafter. ^fAssessed in patients with ADerm-SS TSS-7 ≥ 12 at baseline. ^gAssessed in patients with POEM ≥ 3 at baseline. PBO placebo, UPA upadacitinib