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. 2024 Mar 25;25(3):485–496. doi: 10.1007/s40257-024-00853-4

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 4 — Improvement in daily living, daily activities, and emotional state (observed case [OC]). a Dermatology Life Quality Index (DLQI) improvement ≥ 4.^a b Atopic Dermatitis Impact Scale (ADerm-IS) Daily Activities improvement ≥ 14.^b c ADerm-IS Emotional State improvement ≥ 11.^c d DLQI 0/1.^d e ADerm-IS Daily Activities 0–2.^e f ADerm-IS Emotional State 0–2.^f Error bars indicate 95% confidence interval. ^aAssessed in patients aged ≥ 16 years with DLQI ≥ 4 at baseline. ^bAssessed in patients with ADerm-IS Daily Activities Domain ≥ 14 at baseline. ^cAssessed in patients with ADerm-IS Emotional State ≥ 11 at baseline. ^dAssessed in patients aged ≥ 16 years with DLQI > 1 at baseline. ^eAssessed in patients with ADerm-IS Daily Activities > 3 at baseline. ^fAssessed in patients with ADerm-IS Emotional State > 3 at baseline. PBO placebo, UPA upadacitinib