Table 3:
Studies of postoperative opioid overdose incidence.
| First author | Year | Sample size | Postoperative timeframe | Opioid naïve | Continuous insurance coverage required | Evidence of postoperative opioid fill required | Overdose Incidence | Notes |
|---|---|---|---|---|---|---|---|---|
| Ladha | 2018 | 1,305,715 | 30 days | No* | No | Yes | 0.01% | |
| Aalberg | 2022 | 304,780 | 1 year | Yes | Yes | No | 0.68% | VHA population |
| Siglin | 2020 | 261,208 | 1 year | No | Yes | No | 0.7% | VHA population; colonoscopy included |
| Mudumbai | 2019 | 64,391 | 1 year | No* | Yes | Yes | 0.8% | VHA population |
| Jivraj ** | 2020 | 162,830 | 1 year | Yes | Yes | No | 0.01% | Ontario population |
| Wiese | 2021 | 56,723 | 1 year | Yes | Yes | Yes | 0.05% | |
| Wylie | 2022 | 35,335 | Median 3.5 years | Yes | No | Yes | 0.03% | Single center; included manual record review |
*
Assessed separately
**
Canadian population