Table 2.
Brain regions showing FC changes in adolescents with depression using the ROIs of the prefrontal cortex.
| ROI | Cluster | Brain region | Size | Peak MNI coordinates | T-value | |||
|---|---|---|---|---|---|---|---|---|
| X | Y | Z | ||||||
| Adolescent with Depression< HC | ||||||||
| BA 8 (Eye Field_R) | 1 | Occipital_Mid_R | 244 | 33 | −51 | 30 | 3.8866 | |
| BA 9/46 (DLPFC_L) | 2 | Frontal_Inf_Tri_L | 206 | −36 | 45 | −9 | 3.9095 | |
| BA 11/12 (Orbitofrontal area_R) | 3 | Temporal_Mid_R | 156 | 39 | 27 | 42 | 3.9033 | |
| 4 | Insula_R | 259 | 36 | 30 | 0 | 4.2191 | ||
| 5 | Occipital_Mid_R | 165 | 36 | −78 | 30 | 3.9021 | ||
| BA 13 (Insula_L) | 6 | Calcarine_L | 205 | −18 | −99 | −6 | 3.6676 | |
| BA 24/32 (ACC_R) | 7 | Calcarine_L | 205 | −18 | −99 | 16 | 3.6676 | |
| 8 | Precuneus_R | 170 | 6 | −69 | 45 | 3.8938 | ||
ROI, region of interest; Eye Field_R, right frontal eye field; DLPFC_L, left dorsolateral prefrontal cortex; Orbitofrontal area_R, right orbitofrontal cortex; Insula_L, left insula; Insula_R, right insula; ACC_R, right anterior cingulate cortex; Occipital_Mid_R, right middle occipital gyrus; Frontal_Inf_Tri_L, left triangular part of the inferior frontal gyrus; Occipital_Mid_R, right middle occipital cortex; Temporal_Mid_R, right middle temporal cortex; Calcarine_L, left calcarine; Precuneus_R, right precuneus.