Table 2.
Characteristics of ANA-negative and ANA-positive patients with RA.
| Variables | ANA-negative (n = 289) | ANA-positive (n = 886) | P value |
|---|---|---|---|
| Age (years) | 58.2 (12.7) | 57.1 (13.3) | 0.245 |
| Sex | 0.013 | ||
| Male | 99 (34.26%) | 236 (26.64%) | |
| Female | 190 (65.74%) | 650 (73.36%) | |
| CCP (U/mL) | 53.8 (2.0-200.0) | 200.0 (48.2-200.0) | <0.001 |
| MCV (U/mL) | 37.7 (8.4-682.7) | 461.6 (50.6-1000.0) | <0.001 |
| RF (IU/mL) | 45.7 (10.6-222.5) | 130.0 (28.0-380.0) | <0.001 |
| CRP (mg/L) | 24.1 (5.7-64.8) | 18.9 (6.3-49.1) | 0.038 |
| ESR (mm/hour) | 48.0 (23.0-77.0) | 51.0 (27.0-78.0) | 0.351 |
Abbreviations: RA, rheumatoid arthritis; ANA, antinuclear antibody; CCP, cyclic citrullinated peptide; MCV, mutant citrulline vimentin; RF, rheumatoid factor; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate.