Table 4.
Odds ratio (OR) and 95% confidence interval (CI) for the association between ANA and RA in the propensity-score matched cohort*, took 1:320 and nuclear homogeneous as reference, respectively.
| Variables | Non-adjusted | Adjusted I | ||
|---|---|---|---|---|
| OR (95%CI) | p-value | OR (95%CI) | p-value | |
| ANA titers | ||||
| 1:320 | Reference | Reference | ||
| Negative | 0.06 (0.03, 0.11) | <0.0001 | 0.06 (0.03, 0.11) | <0.0001 |
| 1:100 | 0.24 (0.14, 0.41) | <0.0001 | 0.24 (0.14, 0.42) | <0.0001 |
| 1:1,000 | 1.05 (0.48, 2.27) | 0.9062 | 1.04 (0.48, 2.26) | 0.9163 |
| ANA patterns | ||||
| Nuclear homogeneous | Reference | Reference | ||
| Negative | 0.06 (0.04, 0.09) | <0.0001 | 0.06 (0.04, 0.09) | <0.0001 |
| Nuclear speckled | 0.20 (0.14, 0.30) | <0.0001 | 0.20 (0.14, 0.30) | <0.0001 |
| Centromere | 0.25 (0.04, 1.52) | 0.1319 | 0.25 (0.04, 1.54) | 0.1345 |
| Nucleolar | 0.10 (0.05, 0.20) | <0.0001 | 0.10 (0.05, 0.20) | <0.0001 |
| Cytoplasmic speckled | 0.18 (0.10, 0.34) | <0.0001 | 0.18 (0.10, 0.34) | <0.0001 |
| Other patterns | 0.19 (0.06, 0.60) | 0.0045 | 0.19 (0.06, 0.60) | 0.0046 |
*The propensity-score matched cohort included 598 patients in the RA group and 598 patients in the non-RA group.
RA, rheumatoid arthritis; ANA, antinuclear antibody.
Adjusted I: Adjusted for age, sex.