The comparison of PINK1 levels in the 10 subgroups with different clinical diagnoses. All the subjects in different diagnostic groups were redivided into subgroups according to different factors including Sex (A), Overweight (B), HP (C), DM (D), Smoker (E), Drinker (F), Depression (G), Anxiety (H), CI (I), and RBD (J). *p < 0.05, **p < 0.01. Overweight, subjects with BMI ≥ 24; HP, subjects with high blood pressure; DM subjects with diabetes mellitus; Smoker, subjects who have smoked continuously or cumulatively for 6 months or more in their lifetime; Drinker, subjects who have consumed alcohol continuously or cumulatively for 6 months or more in their lifetime (at least once a week); Anxiety, subjects with possible anxiety or anxiety and HAMA score ≥ 7; Depression, subjects with possible depression or depression and HAMD score ≥ 7; and CI, subjects with cognitive impairment according to MMSE scores (MMSE was used for cognitive examination, with adjustment of the cutoff score for cognitive impairment according to the years of education as follows: illiterate, ≤17 points; primary school education, ≤20 points; and postsecondary education or above, ≤24 points); RBD, subjects with RBDQ-HK >18 points.