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. 2024 Apr 30;45:101934. doi: 10.1016/j.tranon.2024.101934

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© 2024 Published by Elsevier Inc.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 5 — NAT10 promotes M2 polarization in THP-1 cells through enhancing lipid metabolism A. NAT10 was overexpressed in macrophages. B. The expression changes in M2 markers in THP-1-DM co-cultured with ESCC cells after NAT10 overexpression. C–I. The effects of NAT10 overexpression on cellular TG levels (C), fatty acid content (D), FAO levels (E), OCR (F), ECAR (G), ATP levels (H), and lipid droplets (I) in macrophages. J, K. The effects of NAT10 overexpression on the promotion of M2 macrophages (J) and the reduction of M1 macrophages. (K). ^⁎⁎P < 0.01.