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The IC50 values (µM) of OphF, OphU and 5-OH-21-CHO-OphF on A2780, Siha, and MDA-MB-231 cell lines
| A2780 | Siha | MDA-MB-231 | |
|---|---|---|---|
| Ophiobolin F | > 40 | > 40 | > 40 |
| Ophiobolin U | 11.73 ± 0.63 | 40.23 ± 1.37 | > 40 |
| 5-OH-21-CHO-OphF | 1.33 ± 0.54 | 4.64 ± 0.27 | 10.71 ± 0.43 |
| Adriamycin | 1.01 ± 0.13 | N/A | 0.42 ± 0.11 |
| Cisplatin | N/A | 2.79 ± 0.27 | N/A |
Adriamycin and cisplatin used as positive control
